|The TXNRD1 txnrd1 (Catalog #MBS832326) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Thioredoxin Reductase 1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Thioredoxin Reductase 1 can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP).
IP 1-2ul/400ul lysates. Researchers should empirically determine the suitability of the TXNRD1 txnrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TXNRD1 txnrd1 product has the following accession number(s) (GI #37542493) (NCBI Accession #AAL15432.1) (Uniprot Accession #Q16881). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Thioredoxin Reductase 1 antibody with the following immunoassay(s):
Western Blot (WB) ()
Mouse monoclonal Thioredoxin Reductase 1 antibody.
Biological Significance: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Immunogen: Thioredoxin Reductase 1 antibody was raised in Mouse using recombinant human protein purified from E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TXNRD1 are readily searchable from our website. Different antibodies against the same target such as TXNRD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TXNRD1 also interacts with the following gene(s): SEPHS2, TXN. Breast Neoplasms, Cardiovascular Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Lung Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Poisoning are some of the diseases may be linked to Thioredoxin Reductase 1 antibody. The following patways have been known to be associated with this gene.