anti-TYRO3 antibody product blog
Tags: Antibody; Monoclonal Antibody; Tyro3; anti-TYRO3 antibody;
The TYRO3 tyro3 (Catalog #MBS850913) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TYRO3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TYRO3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB: 1:500-1:2000
ELISA: 1:10000
Not yet tested in other applications. Determining optimal working dilutions by titration test. Researchers should empirically determine the suitability of the TYRO3 tyro3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TYRO3 tyro3 product has the following accession number(s) (GI #27597078) (NCBI Accession #NP_006284.2) (Uniprot Accession #Q06418). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TYRO3 Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1. Western blot analysis using TYRO3 mouse mAb against extracellular domain of human TYRO3 (aa41-429).)
TYRO3. Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein. NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
Immunogen: Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TYRO3 are readily searchable from our website. Different antibodies against the same target such as TYRO3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.