|The USP1 usp1 (Catalog #MBS2542110) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The USP1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s USP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).
IHC: 1:20-1:200. Researchers should empirically determine the suitability of the USP1 usp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The USP1 usp1 product has the following accession number(s) (GI #63053522) (NCBI Accession #NP_001017415.1) (Uniprot Accession #O94782). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the USP1 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HepG2 cells using USP1 Monoclonal Antibody at dilution of 1:2000)
USP1(Ubiquitin carboxyl-terminal hydrolase 1) is a negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2.It is Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA.This protein, which consists of 785 amino acids with a deduced molecular mass of 88.2 kDa, possesses His and Cys domains that are highly conserved in all members of the ubiquitin-specific processing (UBP) family of proteases. The USP1 enzyme can undergo autocleavage, resulting in a 100 kDa N-terminal fragment and a 14 kDa C-terminal fragment.
Immunogen: Fusion protein of USP1. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing USP1 are readily searchable from our website. Different antibodies against the same target such as USP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. USP1 also interacts with the following gene(s): FANCD2, FANCI, PCNA, PHLPP1. The following patways have been known to be associated with this gene. Anemia, Cell Transformation, Neoplastic, Infertility, Female, Infertility, Male, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to USP1 Monoclonal Antibody. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Liver, Lung, Nerve, Placenta, Skin tissues are correlated with this protein.