KRT8 antibody product blog
Tags: Antibody; KRT8; Cytokeratin 8/18; KRT8 antibody;
The KRT8 krt8 (Catalog #MBS4380408) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 8/18 reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. MyBioSource\'s Cytokeratin 8/18 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin.FC/FACS: 0.5-1ug/million cells
IF: 1-2ug/ml
WB: 0.5-1.0ug/ml
IHC-F: 0.5-1.0ug/ml for 30 min at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Researchers should empirically determine the suitability of the KRT8 krt8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KRT8 krt8 product has the following accession number(s) (GI #372466577) (NCBI Accession #NP_001243222.1) (Uniprot Accession #P05787). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Cytokeratin 8/18 with the following immunoassay(s):
Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Cytokeratin 8/18 Monoclonal Antibody (KRT8.18/1346).)
Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cytokeratin 8/18 Monoclonal Antibody (KRT8.18/1346).)
Immunogen: Cytoskeleton preparation from HeLa cells
Cellular Localization: Cytoplasmic. Hu-chromosome Location: 17q21.2 (CK8); 12q13.13 (CK18)
Positive Control: MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KRT8 are readily searchable from our website. Different antibodies against the same target such as KRT8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Embryonic Tissue, Eye, Intestine, Kidney, Liver, Lung, Lymph Node, Pancreas, Prostate, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Drug-Induced Liver Injury, Fibrosis, Hepatitis, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasms are some of the diseases may be linked to Cytokeratin 8/18. KRT8 also interacts with the following gene(s): EGFR, FGFR3, KRT18, MAPK1, MAPK3.