anti-Cd101 antibody product blogThe Cd101 cd101 (Catalog #MBS601720) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The CD101 (EWI-101, Glu-Trp-Ile EWI motif-containing protein 101, Gm1016, Gm734, Igsf2, IgSF2, Immunoglobulin superfamily member 2, LOC381460) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD101 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).
Flow Cytometry: Dilute this antibody to 25ug/ml and add 10 L of the diluted solution to 1-2.5 x 10e5 cells in a total reaction volume not exceeding 200 L. The binding of unlabeled monoclonal antibodies may be visualized by adding 10 L of a 25ug/ml stock solution of a secondary developing reagent such as goat anti-rat IgG conjugated to a fluorochrome., Optimal dilutions should be determined by each laboratory for each application. Researchers should empirically determine the suitability of the Cd101 cd101 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Cd101 cd101 product has the following accession number(s) (GI #157390470) (Uniprot Accession #A8E0Y8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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CD101 (EWI-101, Glu-Trp-Ile EWI motif-containing protein 101, Gm1016, Gm734, Igsf2, IgSF2, Immunoglobulin superfamily member 2, LOC381460)
IGSF2, also known as CD101, is an Ig-superfamily transmembrane protein. It is expressed on dendritic cells, Langerhans cells, granulocytes, and activated T cells. IGSF2 ligation is involved in T cell activation. Polymorphisms in IGSF2 are associated with susceptibility to type I diabetes. The extracellular domains of mouse and human IGSF2 share 70% amino acid sequence identity.
Immunogen: rmIGSF2 extracellular domian. Hybridoma: Produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a rat immunized with purified recombinant mouse IGSF2 (rmIGSF2; Accession # BAD97674) extracellular domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Cd101 are readily searchable from our website. Different antibodies against the same target such as Cd101 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Skin tissues are correlated with this protein.