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anti-Lrp4 antibody product blog

Tags: Antibody; Monoclonal Antibody; anti-LRP4 antibody; LRP4;

     The Lrp4 lrp4 (Catalog #MBS800049) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LRP4 (Cytoplasmic) Antibody: FITC reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s LRP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).
1ug/mL (WB). Researchers should empirically determine the suitability of the Lrp4 lrp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Lrp4 lrp4 product has the following accession number(s) (GI #224994223) (NCBI Accession #NP_766256.3) (Uniprot Accession #Q8VI56). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LRP4 (Cytoplasmic) Antibody: FITC with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat Brain Membrane showing detection of ~215 kDa LRP4 protein using Mouse Anti-LRP4 Monoclonal Antibody, Clone S164-6. Lane 1: MW Ladder. Lane 2: Rat Brain Membrane. Load: 10 ug. Block: 5% milk. Primary Antibody: Mouse Anti-LRP4 Monoclonal Antibody at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: TMB solution for 10 min at RT. Predicted/Observed Size: ~215 kDa.)
Western Blot (WB) Lrp4.

Background Info: Detects ~215kDa, small degradation products ~100kD

Scientific Background: Potential cell surface endocytic receptor, which bindsand internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

Conjugate: FITC. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Lrp4 are readily searchable from our website. Different antibodies against the same target such as Lrp4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Multiple, Atrophy, Brain Diseases, Disease Models, Animal, Hyperplasia, Inflammation, Kidney Diseases, Nervous System Diseases, Syndactyly, Tooth Abnormalities are some of the diseases may be linked to LRP4 (Cytoplasmic) Antibody: FITC. Bone, Brain, Embryonic Tissue, Eye tissues are correlated with this protein. The following patways have been known to be associated with this gene.
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